How to get from Naples to Sorrento (come arrivare a Sorrento da Napoli) is one of Italy's most specifically useful single inter-city connections: the Circumvesuviana railway from Napoli Garibaldi to Sorrento (1h05m, €3.30) places the visitor at the gateway to the Amalfi Coast, Capri, Positano, and Ischia in a single 3.30-euro journey. Sorrento (GPS: 40.6264°N, 14.3757°E) is the most specifically strategic single southern Italy base town for the visitor whose program includes the Amalfi Coast and Capri, the specific Sorrento ferry pier connects to all major Amalfi Coast and Bay of Naples destinations, making Sorrento the most specifically efficient single hub for the multi-destination southern Italy coastal program.
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Naples to Sorrento: Step by Step

The Circumvesuviana (Best and Only Practical Option: 1h05m, 3.30€)
The EAV Circumvesuviana from Napoli Garibaldi station (GPS: 40.8524°N, 14.2724°E, underground, below Napoli Centrale): take the SORRENTO LINE (the "Napoli-Sorrento" service, verify the specific destination board above each Circumvesuviana platform entrance before boarding: the 5 different Circumvesuviana lines serve different destinations and the wrong line means a completely different part of the Vesuvius area). Ticket: €3.30 one-way, bought at the blue ticket machines or the Circumvesuviana ticket window (NOT the white Trenitalia machines, those don't sell Circumvesuviana tickets). Journey time: 1h05m-1h12m (10 intermediate stops including Ercolano Scavi for Herculaneum and Pompei Scavi for Pompeii). The specific Sorrento station (GPS: 40.6270°N, 14.3768°E): the Circumvesuviana terminus in the Sorrento Valle dei Mulini (the Mill Valley, the specific excavated valley in the Sorrento limestone where the railway terminates: 5-minute walk up the specific staircase to Piazza Tasso (the main Sorrento piazza) and 8-minute walk to the Sorrento ferry pier).
Why Sorrento as the Amalfi Base
The specific Sorrento base advantages for the Amalfi Coast program: the Sorrento ferry pier (GPS: 40.6268°N, 14.3744°E, the Sorrento ferry pier connects to: Positano (25 min, ~€12). Amalfi (40 min, ~€15). Capri (25 min, ~€15). Ischia (45 min, ~€18). And Procida (40 min, ~€15)). The Sorrento accommodation price (the specific price comparison: a Sorrento 3-star sea-view hotel averages €100-140 per night for a double room in July-August vs the equivalent Positano 3-star at €180-280 per night, a consistent 35-50% accommodation price saving for the identical sea view and ferry-pier access). And the Circumvesuviana direct link to Naples (€3.30, 1h05m) allowing the Naples full-day program as a Sorrento day trip without the stress of the Amalfi Coast road driving.
The Alternative: SITA Bus (Not Recommended)
The SITA bus from Naples to Sorrento via the SS145 coastal road: approximately 2h-3h (traffic-dependent in July-August), approximately €4. Significantly slower, more expensive, and less reliable than the Circumvesuviana for the Naples to Sorrento connection. The SITA bus is useful in the opposite direction for the Sorrento to Naples program if the visitor wants to see the Positano and Amalfi coastal road from the bus window, but for the Naples to Sorrento arrival, the Circumvesuviana is always the better choice.
Q&A: Naples to Sorrento
Is Sorrento worth visiting on its own or only as a base?
Both. Sorrento has its own specific program beyond the hub function: the Marina Grande (GPS: 40.6258°N, 14.3669°E, the specific small original Sorrento fishing harbor: the most specifically authentic single Sorrento experience outside the tourist strip), the Museo Correale di Terranova (GPS: 40.6302°N, 14.3828°E, the most comprehensive single Sorrento decorative arts collection: the specific 17th-18th century Campanian furniture, the specific Capodimonte porcelain, and the specific Neapolitan paintings: admission €8), and the specific Sorrento lemon product shopping (the limoncello (the lemon liqueur from the specific Sorrento Sfusato Amalfitano lemon variety, the most specifically large and aromatic single lemon cultivar in Italy): the Gargiulo & Jannuzzi lemon factory shop (GPS: 40.6283°N, 14.3797°E) has the most specifically authentic single Sorrento limoncello at the most specifically producer-price). Sorrento as a destination rather than only a base is the most specific argument for the 2-night Sorrento program (1 night = hub only; 2 nights = Sorrento town explored + 1 coastal day trip).